α4β2 nicotinic receptor status in Alzheimer's disease using (123)I‐5IA‐85380 single‐photon‐emission computed tomography

BACKGROUND: Loss of the α4β2 nicotinic receptor subtype is found at autopsy in Alzheimer's disease. OBJECTIVE: To investigate in vivo changes in this receptor using single‐photon‐emission CT (SPECT) with (123)I‐5‐iodo‐3‐[2(S)‐2‐azetidinylmethoxy] pyridine (5IA‐85380), a novel nicotinic acetylch...

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Autores principales: O'Brien, J T, Colloby, S J, Pakrasi, S, Perry, E K, Pimlott, S L, Wyper, D J, McKeith, I G, Williams, E D
Formato: Artículo
Lenguaje:English
Publicado: BMJ Group 2007
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Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077777/
https://ncbi.nlm.nih.gov/pubmed/17135460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2006.108209
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2077777/
https://ncbi.nlm.nih.gov/pubmed/17135460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2006.108209

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