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Predicted structure of the extracellular region of ligand-gated ion-channel receptors shows SH2-like and SH3-like domains forming the ligand-binding site.

Fast synaptic neurotransmission is mediated by ligand-gated ion-channel (LGIC) receptors, which include receptors for acetylcholine, serotonin, GABA, glycine, and glutamate. LGICs are pentamers with extracellular ligand-binding domains and form integral membrane ion channels that are selective for c...

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Detalhes bibliográficos
Main Authors: Gready, J. E., Ranganathan, S., Schofield, P. R., Matsuo, Y., Nishikawa, K.
Formato: Artigo
Idioma:English
Publicado em: Cold Spring Harbor Laboratory Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143702/
https://ncbi.nlm.nih.gov/pubmed/9144769
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