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Progress toward the evolution of an organism with an expanded genetic code

Several significant steps have been completed toward a general method for the site-specific incorporation of unnatural amino acids into proteins in vivo. An “orthogonal” suppressor tRNA was derived from Saccharomyces cerevisiae tRNA(2)(Gln). This yeast orthogonal tRNA is not a substrate in vitro or...

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Detalhes bibliográficos
Main Authors: Liu, David R., Schultz, Peter G.
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21768/
https://ncbi.nlm.nih.gov/pubmed/10220370
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