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Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma

We have transfected the mouse CD4 gene into a beef insulin (BI)- specific murine T helper hybridoma that lacks CD4 surface expression. The CD4-expressing transfectants have acquired an additional reactivity for pork insulin (PI), which was not detectable in the original recipient cell. The transfect...

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Detalhes bibliográficos
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188913/
https://ncbi.nlm.nih.gov/pubmed/2965740
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