Pharmacological activators of AMP-activated protein kinase have different effects on Na(+) transport processes across human lung epithelial cells

BACKGROUND AND PURPOSE: AMP-activated protein kinase (AMPK) is activated by metformin, phenformin, and the AMP mimetic, 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR). We have completed an extensive study of the pharmacological effects of these drugs on AMPK activation, adenine nucleoti...

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Main Authors: Woollhead, A M, Sivagnanasundaram, J, Kalsi, K K, Pucovsky, V, Pellatt, L J, Scott, J W, Mustard, K J, Hardie, D G, Baines, D L
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189835/
https://ncbi.nlm.nih.gov/pubmed/17603555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707343
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2189835/
https://ncbi.nlm.nih.gov/pubmed/17603555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707343

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