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Restricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinations
To determine the extent of kappa chain diversity in the preimmune repertoire early in development, kappa cDNA libraries were analyzed from 15-d old fetal omentum, 18-d-old fetal liver, and 3-wk old bone marrow. An anchored polymerase chain reaction approach was used to avoid bias for particular V ka...
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| Formato: | Artigo |
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| Idioma: | English |
| Publicado em: |
The Rockefeller University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190999/ https://ncbi.nlm.nih.gov/pubmed/8478611 |
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