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The P190, P210, and P230 Forms of the BCR/ABL Oncogene Induce a Similar Chronic Myeloid Leukemia–like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity

The product of the Philadelphia chromosome (Ph) translocation, the BCR/ABL oncogene, exists in three principal forms (P190, P210, and P230 BCR/ABL) that are found in distinct forms of Ph-positive leukemia, suggesting the three proteins have different leukemogenic activity. We have directly compared...

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Detalhes bibliográficos
Main Authors: Li, Shaoguang, Ilaria, Robert L., Million, Ryan P., Daley, George Q., Van Etten, Richard A.
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193055/
https://ncbi.nlm.nih.gov/pubmed/10224280
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