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Thymic Medullary Epithelial Cell Differentiation, Thymocyte Emigration, and the Control of Autoimmunity Require Lympho–Epithelial Cross Talk via LTβR

Thymocytes depend on the interaction with thymic epithelial cells for the generation of a diverse, nonautoreactive T cell repertoire. In turn, thymic epithelial cells acquire their three-dimensional cellular organization via instructive signals from developing thymocytes. The nature of these signals...

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Detalhes bibliográficos
Main Authors: Boehm, Thomas, Scheu, Stefanie, Pfeffer, Klaus, Bleul, Conrad C.
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194183/
https://ncbi.nlm.nih.gov/pubmed/12953095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030794
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