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Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
At present little is known of the biochemical machinery controlling transport of newly synthesized lysosomal hydrolases from the trans- Golgi network (TGN) to endosomes. The demonstration that Vps34p (a protein required for targeting soluble hydrolases to the vacuole in Saccharomyces cerevisiae) is...
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| Formato: | Artigo |
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| Idioma: | English |
| Publicado em: |
The Rockefeller University Press
1995
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199969/ https://ncbi.nlm.nih.gov/pubmed/7642698 |
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