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Preferential elimination of CD28(+) T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis

CD28 on T cells provides a potent costimulatory signal for T cell activation. Down-regulation of CD28 on peripheral T cells has been reported in certain clinical conditions, but full studies on the mechanism and biological significance have not been performed. Our extensive phenotype analysis of per...

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Detalhes bibliográficos
Main Authors: KANEKO, H, SAITO, K, HASHIMOTO, H, YAGITA, H, OKUMURA, K, AZUMA, M
Formato: Artigo
Idioma:English
Publicado em: Blackwell Science Inc 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200594/
https://ncbi.nlm.nih.gov/pubmed/8918566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-849.x
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