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Major Histocompatibility Complex Class II Molecules Can Protect from Diabetes by Positively Selecting T Cells with Additional Specificities

Insulin-dependent diabetes is heavily influenced by genes encoded within the major histocompatibility complex (MHC), positively by some class II alleles and negatively by others. We have explored the mechanism of MHC class II–mediated protection from diabetes using a mouse model carrying the rearran...

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Detalhes bibliográficos
Main Authors: Lühder, Fred, Katz, Jonathan, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212118/
https://ncbi.nlm.nih.gov/pubmed/9449718
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