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Disruption of Lymphocyte Function and Signaling in CD45–associated Protein–null Mice

CD45-AP specifically associates with CD45, a protein tyrosine phosphatase essential for lymphocyte differentiation and antigen receptor–mediated signal transduction. CD45 is thought to mediate antigen receptor signaling by dephosphorylating regulatory tyrosine residues on Src family protein tyrosine...

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Detalhes bibliográficos
Main Authors: Matsuda, Akio, Motoya, Satoshi, Kimura, Shioko, McInnis, Renee, Maizel, Abby L., Takeda, Akiko
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212302/
https://ncbi.nlm.nih.gov/pubmed/9607926
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