Cell Apoptosis: Requirement of H2AX in DNA Ladder Formation but not for the Activation of Caspase-3

Immunofluorescence studies have revealed that H2AX is phosphorylated at the sites of DNA double-strand breaks induced by ionizing radiation and is required for recruitment of repair factors into nuclear foci after DNA damage. Therefore the function of H2AX is believed to be associated primarily with...

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Main Authors: Lu, Chengrong, Zhu, Feng, Cho, Yong-Yeon, Tang, Faqing, Zykova, Tatyana, Ma, Wei-ya, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:English
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227311/
https://ncbi.nlm.nih.gov/pubmed/16818236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.023
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2227311/
https://ncbi.nlm.nih.gov/pubmed/16818236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.023

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