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Construction and characterization of a replication-deficient adenovirus expressing rat-soluble interleukin-6 receptor.

BACKGROUND: The pleiotropic cytokine interleukin-6 mediates its multiple effects at the cell level through a multimeric receptor consisting of a binding protein (gp80) and a signal transducer (gp130). A soluble form of gp80 (sIL-6R or gp55) is found released from the surface of cells and appears to...

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Detalhes bibliográficos
Main Authors: Thibault, V., Terlain, B., Graham, F. L., Gauldie, J.
Formato: Artigo
Idioma:English
Publicado em: The Feinstein Institute for Medical Research 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230182/
https://ncbi.nlm.nih.gov/pubmed/9307980
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