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α2β1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell–specific manner
To define the role of the α2β1 integrin in pathologic angiogenesis, we investigated tumor-associated growth and angiogenesis in wild-type and α2-null mice. Our findings reveal that the α2β1 integrin plays an important role in angiogenesis via regulation of VEGFR1 expression. When challenged with B16...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234046/ https://ncbi.nlm.nih.gov/pubmed/18042800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-094680 |
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