Hepatocyte gene therapy in a large animal: A neonatal bovine model of citrullinemia

The development of gene-replacement therapy for inborn errors of metabolism has been hindered by the limited number of suitable large-animal models of these diseases and by inadequate methods of assessing the efficacy of treatment. Such methods should provide sensitive detection of expression in viv...

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Autors principals: Lee, Brendan, Dennis, Julie A., Healy, Peter J., Mull, Benjamin, Pastore, Lucio, Yu, Hung, Aguilar-Cordova, Estuardo, O’Brien, William, Reeds, Peter, Beaudet, Arthur L.
Format: Article
Idioma:en
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22406/
https://ncbi.nlm.nih.gov/pubmed/10097149
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https://ncbi.nlm.nih.gov/pmc/articles/PMC22406/
https://ncbi.nlm.nih.gov/pubmed/10097149

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