Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons

Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit (Rad21) by separase causes cohesin's dissociation from chromosomes and triggers sister-chromatid disj...

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Main Authors: Pauli, Andrea, Althoff, Friederike, Oliveira, Raquel A., Heidmann, Stefan, Schuldiner, Oren, Lehner, Christian F., Dickson, Barry J., Nasmyth, Kim
Formato: Artigo
Idioma:English
Publicado em: Cell Press 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258333/
https://ncbi.nlm.nih.gov/pubmed/18267092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.12.009
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2258333/
https://ncbi.nlm.nih.gov/pubmed/18267092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.12.009

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