The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity

BACKGROUND: Type II DNA topoisomerases (topos) are essential enzymes needed for the resolution of topological problems that occur during DNA metabolic processes. Topos carry out an ATP-dependent strand passage reaction whereby one double helix is passed through a transient break in another. Humans h...

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Main Authors: Meczes, Emma L., Gilroy, Kathryn L., West, Katherine L., Austin, Caroline A.
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262138/
https://ncbi.nlm.nih.gov/pubmed/18335031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001754
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2262138/
https://ncbi.nlm.nih.gov/pubmed/18335031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001754

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