Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs

We have shown previously that, in sheep primary pituitary cells, bone morphogenetic proteins (BMP)-4 inhibits FSHβ mRNA expression and FSH release. In contrast, in mouse LβT2 gonadotrophs, others have shown a stimulatory effect of BMPs on basal or activin-stimulated FSHβ promoter-driven transcriptio...

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Detalhes bibliográficos
Main Authors: Nicol, L, Faure, M-O, McNeilly, J R, Fontaine, J, Taragnat, C, McNeilly, A S
Formato: Artigo
Idioma:English
Publicado em: BioScientifica 2008
Assuntos:
Regular papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262182/
https://ncbi.nlm.nih.gov/pubmed/18310445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0542
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2262182/
https://ncbi.nlm.nih.gov/pubmed/18310445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0542

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