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Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity

Cells that have evolved to produce large quantities of secreted proteins to serve the integrated functions of complex multicellular organisms are equipped to compensate for protein misfolding. Hepatocytes and plasma cells have well developed chaperone and proteasome systems to ensure that secreted p...

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Detalles Bibliográficos
Main Authors: Buxbaum, Joel N., Ye, Zhengyi, Reixach, Natàlia, Friske, Linsey, Levy, Coree, Das, Pritam, Golde, Todd, Masliah, Eliezer, Roberts, Amanda R., Bartfai, Tamas
Formato: Artigo
Idioma:English
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268196/
https://ncbi.nlm.nih.gov/pubmed/18272491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712197105
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