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Interleukin-21 stimulates antigen uptake, protease activity, survival and induction of CD4(+) T cell proliferation by murine macrophages
Interleukin (IL)-21 is a T cell-derived cytokine which uses a heterodimeric receptor, composed of the common γ-chain (CD132) and an IL-21Rα-chain. IL-21 activates lymphoid T and B cells, modulates antibody production but also suppresses maturation of myeloid dendritic cells; however, its role in the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Blackwell Science Inc
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276972/ https://ncbi.nlm.nih.gov/pubmed/18190607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03581.x |
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