Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis

The nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ) is an important regulator of lipid and glucose homeostasis and cellular differentiation. Studies of many cell types in vitro and in vivo have demonstrated that activation of PPARγ can reduce cellular proliferation. We...

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Detalhes bibliográficos
Main Authors: Rosen, Evan D., Kulkarni, Rohit N., Sarraf, Pasha, Ozcan, Umut, Okada, Terumasa, Hsu, Chung-Hsin, Eisenman, Daniel, Magnuson, Mark A., Gonzalez, Frank J., Kahn, C. Ronald, Spiegelman, Bruce M.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230305/
https://ncbi.nlm.nih.gov/pubmed/14517292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7222-7229.2003
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC230305/
https://ncbi.nlm.nih.gov/pubmed/14517292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7222-7229.2003

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