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Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression.

Using transient overexpression and microinjection approaches, we examined SHPTP2's function in growth factor signaling. Overexpression of catalytically inactive SHPTP2 (PTP2CS) but not catalytically inactive SHPTP1, inhibited mitogen-activated protein (MAP) kinase activation and Elk-1 transacti...

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Detalhes bibliográficos
Main Authors: Bennett, A M, Hausdorff, S F, O'Reilly, A M, Freeman, R M, Neel, B G
Formato: Artigo
Idioma:en
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231101/
https://ncbi.nlm.nih.gov/pubmed/8622663
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