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Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1.

Unregulated expression of the transcription factor E2F promotes the G1-to-S phase transition in cultured mammalian cells. However, there has been no direct evidence for an E2F requirement in this process. To demonstrate that E2F is obligatory for cell cycle progression, we attempted to inactivate E2...

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Detalhes bibliográficos
Main Authors: Wu, C L, Classon, M, Dyson, N, Harlow, E
Formato: Artigo
Idioma:en
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231365/
https://ncbi.nlm.nih.gov/pubmed/8668186
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