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Activation of Ca(2+)-dependent proteolysis in skeletal muscle and heart in cancer cachexia

Cachexia is a syndrome characterized by profound tissue wasting that frequently complicates malignancies. In a cancer cachexia model we have shown that protein depletion in the skeletal muscle, which is a prominent feature of the syndrome, is mostly due to enhanced proteolysis. There is consensus on...

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Detalhes bibliográficos
Main Authors: Costelli, P, Tullio, R De, Baccino, F M, Melloni, E
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363832/
https://ncbi.nlm.nih.gov/pubmed/11286475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1696
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