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A phase II study of the bispecific antibody MDX-H210 (anti-HER2 × CD64) with GM-CSF in HER2+ advanced prostate cancer

The proto-oncogene HER2 presents a novel therapeutic target. We report results in 25 patients with HER2+ advanced prostate cancer treated with the bispecific antibody MDX-H210 15 μg m(−2)by intravenous infusion plus GM-CSF 5 μg kg(−1)day(−1)by subcutaneous injection for 4 days repeated weekly for 6...

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Detalhes bibliográficos
Main Authors: James, N D, Atherton, P J, Jones, J, Howie, A J, Tchekmedyian, S, Curnow, R T
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364053/
https://ncbi.nlm.nih.gov/pubmed/11461069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1878
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