High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours

Twenty-five primary retinoblastoma tumours were analysed by real-time quantitative polymerase chain reaction to determine the genomic copy number of the N-MYC gene (2p24) relative to the copy number for REL, B2M, ALB, AF10 and MLL. Twenty-one of these tumours were shown by Comparative Genomic Hybrid...

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Detalhes bibliográficos
Main Authors: Lillington, D M, Goff, L K, Kingston, J E, Onadim, Z, Price, E, Domizio, P, Young, B D
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2002
Assuntos:
Molecular and Cellular Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364265/
https://ncbi.nlm.nih.gov/pubmed/12232763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600532
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2364265/
https://ncbi.nlm.nih.gov/pubmed/12232763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600532

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