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Parasite Burden and CD36-Mediated Sequestration Are Determinants of Acute Lung Injury in an Experimental Malaria Model

Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no model of m...

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Detalhes bibliográficos
Main Authors: Lovegrove, Fiona E., Gharib, Sina A., Peña-Castillo, Lourdes, Patel, Samir N., Ruzinski, John T., Hughes, Timothy R., Liles, W. Conrad, Kain, Kevin C.
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364663/
https://ncbi.nlm.nih.gov/pubmed/18483551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000068
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