Parasite Burden and CD36-Mediated Sequestration Are Determinants of Acute Lung Injury in an Experimental Malaria Model

Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no model of m...

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Hauptverfasser: Lovegrove, Fiona E., Gharib, Sina A., Peña-Castillo, Lourdes, Patel, Samir N., Ruzinski, John T., Hughes, Timothy R., Liles, W. Conrad, Kain, Kevin C.
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364663/
https://ncbi.nlm.nih.gov/pubmed/18483551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000068
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2364663/
https://ncbi.nlm.nih.gov/pubmed/18483551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000068

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