Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients

In a study of 114 epidemiologically linked Zambian transmission pairs, we evaluated the impact of human leukocyte antigen class I (HLA-I)–associated amino acid polymorphisms, presumed to reflect cytotoxic T lymphocyte (CTL) escape in Gag and Nef of the virus transmitted from the chronically infected...

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Detalhes bibliográficos
Main Authors: Goepfert, Paul A., Lumm, Wendy, Farmer, Paul, Matthews, Philippa, Prendergast, Andrew, Carlson, Jonathan M., Derdeyn, Cynthia A., Tang, Jianming, Kaslow, Richard A., Bansal, Anju, Yusim, Karina, Heckerman, David, Mulenga, Joseph, Allen, Susan, Goulder, Philip J.R., Hunter, Eric
Formato: Artigo
Idioma:English
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373834/
https://ncbi.nlm.nih.gov/pubmed/18426987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072457
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2373834/
https://ncbi.nlm.nih.gov/pubmed/18426987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072457

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