Biomarkers and Mechanisms of FANCD2 Function

Genetic or epigenetic inactivation of the pathway formed by the Fanconi anemia (FA) and BRCA1 proteins occurs in several cancer types, making the affected tumors potentially hypersensitive to DNA cross-linkers and other chemotherapeutic agents. It has been proposed that the inability of FA/BRCA-defe...

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Detalhes bibliográficos
Main Authors: Willers, Henning, Kachnic, Lisa A., Luo, Chen-Mei, Li, Li, Purschke, Martin, Borgmann, Kerstin, Held, Kathryn D., Powell, Simon N.
Formato: Artigo
Idioma:English
Publicado em: Hindawi Publishing Corporation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375970/
https://ncbi.nlm.nih.gov/pubmed/18483568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/821529
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2375970/
https://ncbi.nlm.nih.gov/pubmed/18483568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/821529

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