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Different mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancers
The ERBB2 gene is overexpressed in 30% of breast cancers and this has been correlated with poor prognosis. ERBB2 is upregulated in other cancers such as prostate, pancreas, colon and ovary. In breast cancer cells, the mechanisms leading to ERBB2 gene overexpression are increased transcription and ge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394491/ https://ncbi.nlm.nih.gov/pubmed/12942124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601200 |
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