Pharmacological Blockade of A(2A) Receptors Prevents Dermal Fibrosis in a Model of Elevated Tissue Adenosine

Adenosine is a potent modulator of inflammation and tissue repair. We have recently reported that activation of adenosine A(2A) receptors promotes collagen synthesis by human dermal fibroblasts and that blockade or deletion of this receptor in mice protects against bleomycin-induced dermal fibrosis,...

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Detalhes bibliográficos
Main Authors: Fernández, Patricia, Trzaska, Sean, Wilder, Tuere, Chiriboga, Luis, Blackburn, Michael R., Cronstein, Bruce N., Chan, Edwin S. L.
Formato: Artigo
Idioma:English
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408426/
https://ncbi.nlm.nih.gov/pubmed/18467695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070952
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2408426/
https://ncbi.nlm.nih.gov/pubmed/18467695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070952

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