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Folding of Gas-Phase Polyalanines in a Static Electric Field: Alignment, Deformations, and Polarization Effects

Monte Carlo simulations of the temperature-induced unfolding of small gas-phase polyalanines in a static, homogeneous electric field are reported, based on the AMBER ff96 force field. The peptides exhibit a structural transition from the native α-helix state to entropically favored β-sheet conformat...

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Detalhes bibliográficos
Main Authors: Calvo, F., Dugourd, P.
Formato: Artigo
Idioma:English
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426642/
https://ncbi.nlm.nih.gov/pubmed/18223004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124685
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