Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis

Osteoarthritis (OA), the most prevalent form of arthritis in the elderly, is characterized by the degradation of articular cartilage and has a strong genetic component. Our aim was to identify genetic variants involved in risk of knee OA in women. A pooled genome-wide association scan with the Illum...

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Detalhes bibliográficos
Main Authors: Valdes, Ana M., Loughlin, John, Timms, Kirsten M., van Meurs, Joyce J.B., Southam, Lorraine, Wilson, Scott G., Doherty, Sally, Lories, Rik J., Luyten, Frank P., Gutin, Alexander, Abkevich, Victor, Ge, Dongliang, Hofman, Albert, Uitterlinden, André G., Hart, Deborah J., Zhang, Feng, Zhai, Guangju, Egli, Rainer J., Doherty, Michael, Lanchbury, Jerry, Spector, Tim D.
Formato: Artigo
Idioma:English
Publicado em: American Society of Human Genetics 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427208/
https://ncbi.nlm.nih.gov/pubmed/18471798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.04.006
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2427208/
https://ncbi.nlm.nih.gov/pubmed/18471798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.04.006

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