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Immunoenhancing properties and antiviral activity of 7-deazaguanosine in mice.

The nucleotide analog 7-deazaguanosine has not previously been reported to possess biological (antiviral or antitumor) properties in cell culture or in vivo. Up to 10(5) U of interferon per ml was detected in mouse sera 1 to 4 h following oral (200-mg/kg of body weight) and intraperitoneal (50-mg/kg...

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Detalhes bibliográficos
Main Authors: Smee, D F, Alaghamandan, H A, Gilbert, J, Burger, R A, Jin, A, Sharma, B S, Ramasamy, K, Revankar, G R, Cottam, H B, Jolley, W B
Formato: Artigo
Idioma:en
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC244957/
https://ncbi.nlm.nih.gov/pubmed/1707603
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