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Patterned library analysis: A method for the quantitative assessment of hypotheses concerning the determinants of protein structure

Site-directed mutagenesis and combinatorial libraries are powerful tools for providing information about the relationship between protein sequence and structure. Here we report two extensions that expand the utility of combinatorial mutagenesis for the quantitative assessment of hypotheses about the...

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Detalhes bibliográficos
Main Authors: Lahr, Steven J., Broadwater, Anne, Carter, Charles W., Collier, Martha L., Hensley, Lucinda, Waldner, Jennifer C., Pielak, Gary J., Edgell, Marshall Hall
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24738/
https://ncbi.nlm.nih.gov/pubmed/10611303
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