A bcr-3 isoform of RARα-PML potentiates the development of PML-RARα-driven acute promyelocytic leukemia

Acute promyelocytic leukemia (APML) most often is associated with the balanced reciprocal translocation t(15;17) (q22;q11.2) and the expression of both the PML-RARα and RARα-PML fusion cDNAs that are formed by this translocation. In this report, we investigated the biological role of a bcr-3 isoform...

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Autors principals: Pollock, Jessica L., Westervelt, Peter, Kurichety, Arun K., Pelicci, Pier Giuseppe, Grisolano, Jay L., Ley, Timothy J.
Format: Article
Idioma:en
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24780/
https://ncbi.nlm.nih.gov/pubmed/10611345
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https://ncbi.nlm.nih.gov/pmc/articles/PMC24780/
https://ncbi.nlm.nih.gov/pubmed/10611345

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