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A PI3K Pathway Mediates Hair Cell Survival and Opposes Gentamicin Toxicity in Neonatal Rat Organ of Corti

Gentamicin is well known to promote hair cell death in inner ear, but it also appears to activate opposing pathways that promote hair cell survival. In combination with others, our previous work has indicated that a K-Ras/Rac/JNK pathway is important for hair cell death and an H-Ras/Raf/MEK/Erk path...

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Detalhes bibliográficos
Main Authors: Chung, Won-Ho, Pak, Kwang, Lin, Bo, Webster, Nicholas, Ryan, Allen F.
Formato: Artigo
Idioma:English
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504631/
https://ncbi.nlm.nih.gov/pubmed/17053865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-006-0050-y
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