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Myriaporone 3/4 structure–activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis

Myriaporones are naturally occurring compounds which structurally resemble the southern hemisphere of the tedanolide family of macrolide antitumor agents. Despite the fact that myriaporone 3/4 represents only a portion of tedanolide, it nonetheless retains much of its biological activity. We show he...

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Detalhes bibliográficos
Main Authors: Hines, John, Roy, Myriam, Cheng, Hua, Agapakis, Christina M., Taylor, Richard, Crews, Craig M.
Formato: Artigo
Idioma:English
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507749/
https://ncbi.nlm.nih.gov/pubmed/16880957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b602936a
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