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Cooperative binding mode of the inhibitors of R6K replication, π dimers
The replication initiator protein, π, plays an essential role in the initiation of replication of plasmid R6K. Both monomers and dimers of π bind to iterons in the γ origin of plasmid R6K, yet monomers facilitate open complex formation while dimers, the predominant form in the cell, do not. Conseque...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518315/ https://ncbi.nlm.nih.gov/pubmed/18295232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.039 |
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