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Effect of Carbohydrate Position on Lysosomal Transport of Procathepsin L

To study the role of carbohydrate in lysosomal protein transport, we engineered two novel glycosylation signals (Asn-X-Ser/Thr) into the cDNA of human procathepsin L, a lysosomal acid protease. We constructed six mutant cDNAs encoding glycosylation signals at mutant sites Asn-138, Asn-175, or both s...

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Detalhes bibliográficos
Main Authors: Lingeman, Robert G., Joy, Darrin S., Sherman, Mark A., Kane, Susan E.
Formato: Artigo
Idioma:en
Publicado em: The American Society for Cell Biology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25336/
https://ncbi.nlm.nih.gov/pubmed/9571245
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