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Molecular Recognition Via Triplex Formation of Mixed Purine/Pyrimidine DNA Sequences Using oligoTRIPs
Stable DNA triple helical structures are normally restricted to homopurine sequences. We have described a system of four heterocyclic bases (TRIPsides) that when incorporated into oligomers (oligoTRIPs) can recognize and bind in the major groove to any native sequence of DNA [Li et al., J. Am. Chem....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533713/ https://ncbi.nlm.nih.gov/pubmed/16144414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0530218 |
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