In Vitro-In Vivo Model for Evaluating the Antiviral Activity of Amprenavir in Combination with Ritonavir Administered at 600 and 100 Milligrams, Respectively, Every 12 Hours

The study objective was to evaluate the pharmacodynamics of amprenavir in an in vitro system, develop an exposure target for maximal viral suppression, and determine the likelihood of target attainment based on the pharmacokinetics of amprenavir and ritonavir in human immunodeficiency virus (HIV)-in...

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Detalhes bibliográficos
Main Authors: Preston, Sandra L., Piliero, Peter J., Bilello, John A., Stein, Daniel S., Symonds, William T., Drusano, George L.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2003
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253808/
https://ncbi.nlm.nih.gov/pubmed/14576093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3393-3399.2003
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https://ncbi.nlm.nih.gov/pmc/articles/PMC253808/
https://ncbi.nlm.nih.gov/pubmed/14576093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3393-3399.2003

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