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Plasminogen Activator Inhibitor 1 Protects Fibrosarcoma Cells from Etoposide-Induced Apoptosis through Activation of the PI3K/Akt Cell Survival Pathway

High levels of plasminogen activator inhibitor (PAI-1) in tumors are associated with poor prognosis in several cancer types, and the reason for this association is not fully understood. Plasminogen activator inhibitor 1 has been suggested to contribute to tumor growth by protecting cancer cells from...

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Detalhes bibliográficos
Main Authors: Rømer, Maria U, Larsen, Lise, Offenberg, Hanne, Brünner, Nils, Lademann, Ulrik A
Formato: Artigo
Idioma:English
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546595/
https://ncbi.nlm.nih.gov/pubmed/18813358
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