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Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

Tuberculosis (TB) is characterized by a tight interplay between Mycobacterium tuberculosis and host cells within granulomas. These cellular aggregates restrict bacterial spreading, but do not kill all the bacilli, which can persist for years. In-depth investigation of M. tuberculosis interactions wi...

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Detalhes bibliográficos
Main Authors: Peyron, Pascale, Vaubourgeix, Julien, Poquet, Yannick, Levillain, Florence, Botanch, Catherine, Bardou, Fabienne, Daffé, Mamadou, Emile, Jean-François, Marchou, Bruno, Cardona, Pere-Joan, de Chastellier, Chantal, Altare, Frédéric
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575403/
https://ncbi.nlm.nih.gov/pubmed/19002241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000204
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