A Functional Genomic Fingerprint of Chronic Stress in Humans: Blunted Glucocorticoid and Increased NF-κB Signaling

BACKGROUND: Chronic stressors are known to increase vulnerability to medical illness, but the mechanisms underlying this phenomenon are poorly understood. METHODS: To identify transcriptional control pathways that are modified by chronic stress, we conducted genome-wide expression microarrays on fam...

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Main Authors: Miller, Gregory E., Chen, Edith, Sze, Jasmen, Marin, Teresa, Arevalo, Jesusa M. G., Doll, Richard, Ma, Roy, Cole, Steve W.
Formato: Artigo
Idioma:English
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581622/
https://ncbi.nlm.nih.gov/pubmed/18440494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.03.017
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2581622/
https://ncbi.nlm.nih.gov/pubmed/18440494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.03.017

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