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A Functional Genomic Fingerprint of Chronic Stress in Humans: Blunted Glucocorticoid and Increased NF-κB Signaling
BACKGROUND: Chronic stressors are known to increase vulnerability to medical illness, but the mechanisms underlying this phenomenon are poorly understood. METHODS: To identify transcriptional control pathways that are modified by chronic stress, we conducted genome-wide expression microarrays on fam...
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| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581622/ https://ncbi.nlm.nih.gov/pubmed/18440494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.03.017 |
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