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Cellular Transcription Factors Sp1 and Sp3 Suppress Varicella-Zoster Virus Origin-Dependent DNA Replication

The varicella-zoster virus (VZV) origin of DNA replication (oriS) contains a 46-bp AT-rich palindrome and three consensus binding sites for the VZV origin binding protein (OBP) encoded by VZV ORF51. All three OBP binding sites are upstream of the palindrome in contrast to the sequence of the herpes...

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Bibliografske podrobnosti
Main Authors: Khalil, Mohamed I., Hay, John, Ruyechan, William T.
Format: Artigo
Jezik:English
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583665/
https://ncbi.nlm.nih.gov/pubmed/18815296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01322-08
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