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Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells.

Our previous work suggests that one mechanism through which connective tissue breakdown might occur in periodontal diseases is the production of metalloproteinases, including collagenase, by gingival fibroblasts. In this study we investigated whether highly purified preparations of lipopolysaccharid...

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Detalhes bibliográficos
Main Authors: Heath, J K, Atkinson, S J, Hembry, R M, Reynolds, J J, Meikle, M C
Formato: Artigo
Idioma:en
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC260671/
https://ncbi.nlm.nih.gov/pubmed/3040590
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